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Any suggestions when you take possession, appliances don't work, damage to interior and seller says oh well.

That's what you pay your realtor and lawyer for. They should be able to get something for you. Although if older appliances they'd only be responsible to replace with something of equal value not something brand new.

Don't talk to the seller. It needs to be in good working condition.  
 
Talk to your realtor/lawyer.

What does your offer say- in good working condition or as is?

Did you have a home inspection done? Allows for testing appliances and home is purchased by you as is or at time of inspection which you sign that you're happy. Contract will say a seller must keep home in same condition until possession with your signature.  
 
Unless it was a private sale, you should be covered by the contract, home inspection, the realtors and your lawyer.

Yeah, talk to the realtor of there was one used. We had a rental property we sold years ago, and the tenant didn't tell us the stove was broken (or it quit right around time of possession, we're not sure which). The realtor came back to us and we paid for a new second-had one (I think we agreeded on the price beforehand, and then the lawyer sent the money and it just got rolled into our costs).  
 
In short, like others have said, the property should be more or less in the dame condition as when you bought it, unless your contract states otherwise. Start with your realtor, then kove on to the lawyer.

Yes realtor has tried, lawyer sending letter but sellers ignoring. Have learned, should have done home inspection. Expensive lessons

I'm sorry you're going through that. An inspection isn't the be-all-end-all, however - we had problems with our current house that wasn't picked up on inspection, and should have been disclosed by the vendor. We taked to a lawyer about it, but the burden of proof was so high, it wasn't worth the money to go after them and we ended up eating the costs and just fixed it.  
 
I hope you end up having a better resolution than us.

We bought our house sixteen years ago and have ended up spending thousands on bringing things up to code. Stuff the home inspection missed as well. TI hope you can find a better resolution than we did.

All appliances must be in working order as well as in the condition in which you viewed it. Only exception is if it was stated in the offer, and was agreed upon! A vendor must disclose any problems as well, if I’m not mistaken you can void the sale if this isn’t done!

Your lawyer should be able to contact the seller's lawyer, who will then take some of the money he has in trust and send it to your lawyer. When you take possession and find a problem like this, call your lawyer immediately so he can contact the other lawyer before the money all gets disbursed. On some deals you don't get much time.

Your realtor should add in offer letter "Possession day, appliances are in working order"

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